An international survey published in JAMA Network Open revealed that cannabis and psychedelics such as psilocybin and LSD were perceived as more effective in relieving symptoms of eating disorders than traditional prescription medications.
The study was conducted by a research team from the University of Sydney, led by PhD candidate Sarah-Catherine Rodan from the Lambert Initiative for Cannabinoid Therapeutics, and is considered the most comprehensive to date in this field.
7,600 Voices: A Look Into Lived Experiences
The research analyzed responses from 7,600 individuals with eating disorders, 94% of whom were women, across 83 countries. Participants reported on their use of prescription and non-prescription substances to manage symptoms.
Among respondents:
40% had anorexia nervosa.
19% had bulimia nervosa.
11% had a binge-eating disorder
9% had ARFID (avoidant/restrictive food intake disorder)
65% reported depression, and 55% reported generalized anxiety
Other commonly reported comorbid conditions included:
ADHD: 33%
Substance use disorder: 15%
Alcoholism: 9%
Top-Rated: Cannabis, Shrooms & LSD Take the Crown
The survey explored which substances people with eating disorders use with or without medical supervision and how they perceive their effects on symptoms and overall mental health.
The findings were clear: cannabis, psilocybin (the active compound in magic mushrooms), and LSD were rated highest for reducing eating disorder symptoms, especially in cases of anorexia and ARFID.
Cannabis: Highly rated for stimulating appetite and enhancing the pleasurable experience of eating—central issues in restrictive disorders. Prior research shows it activates the medial hypothalamus, a brain region associated with hunger and food enjoyment. However, in individuals with bulimia, the effect was not as positive: it may even worsen behaviors like bingeing or compulsive eating.
Psilocybin: This hallucinogenic mushroom compound was reported to help with emotional regulation and reduce eating disorder symptoms. Although use was infrequent (1–2 times per year), many respondents noted long-lasting effects, including improvements in anxiety, mood, and body image.
LSD: Also used …
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Author: Camila Berriex / High Times
