Researchers analyzing two ancient skeletons from Indonesia found dramatic dental wear and traces of arecoline, suggesting people may have sucked psychoactive areca nuts as far back as 25,000 years ago. The finding could represent the earliest known evidence of psychoactive plant use, while also shedding light on a practice that remains widespread today despite serious… Keep Reading
A preclinical study found that repeated CBG treatment prevented a long-term recognition memory impairment induced by MK-801 in male rats, an experimental model used to study cognitive deficits relevant to schizophrenia. The effect did not appear to involve restoring reduced BDNF protein levels, though changes in TrkB messenger RNA point to a possible mechanism that… Keep Reading
A four-person Johns Hopkins pilot study found that 25 mg of oral THC could produce altered-state profiles that qualitatively resembled those seen with 25 mg of psilocybin, particularly when consumed in a setting modeled on psychedelic research. The sample is far too small to establish cannabis as a psychedelic, but the findings add to earlier… Keep Reading
Researchers hooked a flowmeter to pre-rolls at social smoke sessions in five states and found three distinct ways people pull on a joint. All three moved more smoke than the cigarette settings cannabis research has been running for decades. Researchers found three ways people smoke a joint, and you are almost certainly one of them.… Keep Reading
Legalization promised a future for small growers. In Michigan, one would-be craft operator found a market built for speed, scale, and deep pockets. Growing up in the late 1980s and early 1990s, I remember a local police officer from the D.A.R.E. program coming into my elementary school classroom with a high school football player who… Keep Reading
New research found that cannabis stimulates appetite in both rats and humans, suggesting the munchies are driven by shared biological mechanisms rather than culture or expectation. The findings could help scientists better understand appetite regulation and explore future treatments for conditions involving nausea, weight loss, or reduced food intake, while highlighting the need for further… Keep Reading
A fossilized leaf imprint found near Eisleben, Germany may be 56 million years old, doubling the previously accepted timeline for the Cannabis genus and raising new questions about where the plant actually came from. Researchers say further investigation is underway. The implications are enormous either way. It had been sitting in a museum drawer for… Keep Reading
A PAX-authored study comparing vaporized cannabis to joint smoke found significantly lower levels of certain compounds under controlled lab conditions. A new research paper is adding fresh data to a long-running question in cannabis consumption: how vaporizing compares to smoking when it comes to chemical exposure. The research—conducted by Richard Rucker, who serves as PAX’s… Keep Reading
A new survey commissioned by Royal Queen Seeds found cannabis consumers are deeply concerned about pesticides, broadly supportive of home grow and increasingly willing to choose cleaner weed over stronger weed. The weed industry has spent years training people to chase one thing: higher THC. That pitch may be getting old. A new Harris Poll… Keep Reading
A new ProPublica investigation found that Colorado banned chemically converted intoxicating hemp on paper, but weak testing rules, enforcement gaps and industry carve-outs still allowed questionable products to reach consumers through the country’s oldest legal marijuana market. Colorado did not fail because legal weed was a bad idea. Colorado failed because regulators left the door… Keep Reading
