Research Shows Terpenes Can Help Treat Pain Caused by Chemo Medications

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A new study released earlier this month on May 2 in the research journal Pain suggests that an injection of cannabis terpenes is “roughly equal” to the number of pain reduction markers from an injection of morphine.

“Terpenes from Cannabis sativa induce antinociception in a mouse model of chronic neuropathic pain via activation of adenosine A2A receptors” features researchers hailing from multiple departments at the University of Arizona as well as with awarded funding from the National Institutes of Health.

Researchers sought out to see how cannabis can potentially treat chronic pain. “A question that we’ve been very interested in is could terpenes be used to manage chronic pain?” said John Streicher, PhD, who is the lead author of the study. “What we found is that terpenes are really good at relieving a specific type of chronic pain with side effects that are low and manageable.”

While both CBD and THC have been found to be beneficial in treating chronic pain, researchers explained that the effects are moderate, and “can come with unwanted psychoactive side effects.” Terpenes are a path around the use of psychoactive substances, which “offer an alternative path to pain relief without adverse side effects.”

For the purpose of this study, researchers examined five different terpenes: alpha-humulene, beta-caryophyllene, beta-pinene, geraniol, and linalool. Researchers utilized a mouse model focused on neuropathic pain, which is a well-known condition that stems from nerve damage caused by chemotherapy medications.

Each terpene was tested on its own and the results were compared with morphine as well. All five terpenes showed significant pain reduction “near to or above the peak effect of morphine” individually, and even more powerful effects on pain when combined. “That was really striking to us, but just because something relieves pain doesn’t necessarily mean it’s going …

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Author: Nicole Potter / High Times

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